Mark M. Davis - Wikipedia

Mark Morris Davis (born 27 November 1952) is director and Avery Family Professor of Immunology in the Institute for Immunity, Transplantation and Infection at Stanford University.


Education

Davis was educated at Johns Hopkins University and the California Institute of Technology (Caltech) where he was awarded a PhD in 1981 for research supervised by Leroy E. Hood.

Research

Davis is well known for identifying the first T-cell receptor genes, which are responsible for T lymphocytes ability to "see" foreign entities, solving a major mystery in immunology at that time. He and his research group have made many subsequent discoveries about this type of molecule, subsequently, specifically concerning its biochemical properties and other characteristics, including the demonstration that T cells are able to detect and respond to even a single molecule of their ligand-fragments of antigens bound to Major Histocompatibility Complex cell surface molecules. He also developed a novel way of labeling specific T lymphocytes according to the molecules that they recognize, and this procedure is now an important method in many clinical and basic studies of T cell activity, from new vaccines against cancer to identifying "rogue" T cells in autoimmunity. In recent years his has increasingly focused on understanding the human immune system, from developing broad systems biology approaches to inventing new methods to help unravel the complexities of T cell responses to cancer, autoimmunity and infectious diseases.


https://en.wikipedia.org/wiki/Mark_M._Davis




Comments

Post a Comment

Popular posts from this blog

Interview of Elisabeth Bik – Scientific Editorial Director at uBiome

Image
"uBiome is the leader in microbial genomics. We develop microbiome products for both consumers as well as for patients and clinicians.  We have developed two clinical products, SmartGut for gastrointestinal conditions, and SmartJane, which combines vaginal microbiome analysis with STI and HPV genotyping. These clinical products are clinician-prescribed and are reimbursable by most health insurance companies." Elisabeth Bik
Read more

The troll Leonid Schneider & ‘For Better Science’: crank or cure?

Image
I’ve been aware of Leonid Schneider’s expose blog ever since the piece on the supposed  fraud of Nobel prize-winner Gregg Semenza  appeared on my Twitter feed. Schneider portrays himself as an  under-dog ; the self-styled “ failed scientist ” has taken a liking to pillaring the hypocrisies of the scientific establishment. To be honest, although criticisms of the undertakings of science are always needed, especially when it concerns matters of data integrity, publishing practices, and perverse incentives in academia, I am a bit weary of uncritically listening to someone who appears to have no established career in either science or science journalism (the only pieces published under his own name appear only on the blog he runs). And his pieces do come off with a bit of crankiness.
Read more